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| Acetone cyanohydrin | CAS 75-86-5 | ||
| CH3C(OH)CNCH3 | RTECS OD9275000 | ||
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Synonyms & Trade Names Cyanohydrin-2-propanone, 2-Cyano-2-propanol, alpha-Hydroxyisobutyronitrile, 2-Hydroxy-2-methyl-propionitrile, 2-Methyllactonitrile |
DOT ID & Guide 1541 155 (stabilized) |
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Exposure Limits |
NIOSH REL: C 1 ppm (4 mg/m3) [15-minute] | ||
| OSHA PEL: none | |||
| IDLH N.D. | Conversion 1 ppm = 3.48 mg/m3 | ||
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Physical Description Colorless liquid with a faint odor of bitter almond. [Note: Forms cyanide in the body.] |
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MW: 85.1 |
BP: 203°F |
FRZ: -4°F |
Sol: Miscible |
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VP: 0.8 mmHg |
IP: ? |
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Sp.Gr(77°F): 0.93 |
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Fl.P: 165°F |
UEL: 12.0% |
LEL: 2.2% |
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| Class IIIA Combustible Liquid: Fl.P. at or above 140�F and below 200�F. | |||
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Incompatibilities & Reactivities Sulfuric acid, caustics [Note: Slowly decomposes to acetone & HCN at room temperatures; rate is accelerated by an increase in pH, water content, or temperature.] |
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Measurement Methods NIOSH 2506 |
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Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated Remove: When wet or contaminated Change: No recommendation Provide: Eyewash, Quick drench |
First Aid (See procedures) Eye: Irrigate immediately Skin: Water flush immediately Breathing: Respiratory support Swallow: Medical attention immediately |
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Respirator Recommendations
NIOSH Up to 10 ppm: (APF = 10) Any supplied-air respirator Up to 25 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode Up to 50 ppm: (APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece Up to 250 ppm: (APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus |
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| Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact | |
| Symptoms Irritation eyes, skin, respiratory system; dizziness, lassitude (weakness, exhaustion), headache, confusion, convulsions; liver, kidney injury; pulmonary edema, asphyxia | |
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Target Organs
Eyes, skin, respiratory system, central nervous system, cardiovascular system, liver, kidneys, gastrointestinal tract |
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| See also: INTRODUCTION |