NIOSH Pocket Guide to Chemical Hazards

Acrylamide CAS 79-06-1
CH2=CHCONH2 RTECS AS3325000
Synonyms & Trade Names
Acrylamide monomer, Acrylic amide, Propenamide, 2-Propenamide
DOT ID & Guide
2074 153P
Exposure
Limits
NIOSH REL: Ca TWA 0.03 mg/m3 [skin] See Appendix A
OSHA PEL�: TWA 0.3 mg/m3 [skin]
IDLH Ca [60 mg/m3] Conversion
Physical Description
White crystalline, odorless solid.
MW: 71.1
BP: 347-572°F (Decomposes)
MLT: 184°F
Sol(86°F): 216%
VP: 0.007 mmHg
IP: 9.50 eV

Sp.Gr: 1.12
Fl.P: 280°F
UEL: ?
LEL: ?

Combustible Solid (may also be dissolved in flammable liquids).
Incompatibilities & Reactivities
Strong oxidizers [Note: May polymerize violently upon melting.]
Measurement Methods
OSHA 21, PV2004
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Water flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin; ataxia, numb limbs, paresthesia; muscle weakness; absent deep tendon reflex; hand sweating; lassitude (weakness, exhaustion), drowsiness; reproductive effects; [potential occupational carcinogen]
Target Organs Eyes, skin, central nervous system, peripheral nervous system, reproductive system

Cancer Site [in animals: tumors of the lungs, testes, thyroid & adrenal glands]
See also: INTRODUCTION